- Highly Complementary Portfolios with Leading Franchises in Oncology, Immunology and Inflammation and Cardiovascular Disease
- Significantly Expands Phase III Assets with Six Expected Near-Term Product Launches, Representing Greater Than $15 Billion in Revenue Potential
- Registrational Trial Opportunities and Early-Stage Pipeline Position Combined Company for Sustained Leadership Underpinned by Cutting-Edge Technologies and Discovery Platforms
- Strong Combined Cash Flows, Enhanced Margins and EPS Accretion of Greater Than 40% in First Full Year
- Approximately $2.5 Billion of Expected Run-Rate Cost Synergies to Be Achieved by 2022
NEW YORK & SUMMIT, N.J.,--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) and Celgene Corporation
(NASDAQ:CELG) today announced that they have entered into a definitive
merger agreement under which Bristol-Myers Squibb will acquire Celgene
in a cash and stock transaction with an equity value of approximately
$74 billion. Under the terms of the agreement, Celgene shareholders will
receive 1.0 Bristol-Myers Squibb share and $50.00 in cash for each share
of Celgene. Celgene shareholders will also receive one tradeable
Contingent Value Right (CVR) for each share of Celgene, which will
entitle the holder to receive a payment for the achievement of future
regulatory milestones. The Boards of Directors of both companies have
approved the combination.
The transaction will create a leading focused specialty biopharma
company well positioned to address the needs of patients with cancer,
inflammatory and immunologic disease and cardiovascular disease through
high-value innovative medicines and leading scientific capabilities.
With complementary areas of focus, the combined company will operate
with global reach and scale, maintaining the speed and agility that is
core to each company’s strategic approach.
Based on the closing price of Bristol-Myers Squibb stock of $52.43 on
January 2, 2019, the cash and stock consideration to be received by
Celgene shareholders at closing is valued at $102.43 per Celgene share
and one CVR (as described below). When completed, Bristol-Myers Squibb
shareholders are expected to own approximately 69 percent of the
company, and Celgene shareholders are expected to own approximately 31
percent.
“Together with Celgene, we are creating an innovative biopharma leader,
with leading franchises and a deep and broad pipeline that will drive
sustainable growth and deliver new options for patients across a range
of serious diseases,” said Giovanni Caforio, M.D., Chairman and Chief
Executive Officer of Bristol-Myers Squibb. “As a combined entity, we
will enhance our leadership positions across our portfolio, including in
cancer and immunology and inflammation. We will also benefit from an
expanded early- and late-stage pipeline that includes six expected
near-term product launches. Together, our pipeline holds significant
promise for patients, allowing us to accelerate new options through a
broader range of cutting-edge technologies and discovery platforms.”
Dr. Caforio continued, “We are impressed by what Celgene has
accomplished for patients, and we look forward to welcoming Celgene
employees to Bristol-Myers Squibb. Our new company will continue the
strong patient focus that is core to both companies’ missions, creating
a shared organization with a goal of discovering, developing and
delivering innovative medicines for patients with serious diseases. We
are confident we will drive value for shareholders and create
opportunities for employees.”
“For more than 30 years, Celgene’s commitment to leading innovation has
allowed us to deliver life-changing treatments to patients in areas of
high unmet need. Combining with Bristol-Myers Squibb, we are delivering
immediate and substantial value to Celgene shareholders and providing
them meaningful participation in the long-term growth opportunities
created by the combined company,” said Mark Alles, Chairman and Chief
Executive Officer of Celgene. “Our employees should be incredibly proud
of what we have accomplished together and excited for the opportunities
ahead of us as we join with Bristol-Myers Squibb, where we can further
advance our mission for patients. We look forward to working with the
Bristol-Myers Squibb team as we bring our two companies together.”
Compelling Strategic Benefits
-
Leading franchises with complementary product portfolios provide
enhanced scale and balance. The combination creates:
-
Leading oncology franchises in both solid tumors and hematologic
malignancies led by Opdivo and Yervoy as well as Revlimid and
Pomalyst;
-
A top five immunology and inflammation franchise led by Orencia
and Otezla; and
-
The #1 cardiovascular franchise led by Eliquis.
The combined company will have nine products with more than $1 billion
in annual sales and significant potential for growth in the core disease
areas of oncology, immunology and inflammation and cardiovascular
disease.
-
Near-term launch opportunities representing greater than $15
billion in revenue potential. The combined company will have six
expected near-term product launches:
-
Two in immunology and inflammation, TYK2 and ozanimod; and
-
Four in hematology, luspatercept, liso-cel (JCAR017), bb2121 and
fedratinib.
These launches leverage the combined commercial capabilities of the two
companies and will broaden and enhance Bristol-Myers Squibb’s market
position with innovative and differentiated products. This is in
addition to a significant number of lifecycle management registrational
readouts expected in Immuno-Oncology (IO).
-
Early-stage pipeline builds sustainable platform for growth. The
combined company will have a deep and diverse early-stage pipeline
across solid tumors and hematologic malignancies, immunology and
inflammation, cardiovascular disease and fibrotic disease leveraging
combined strengths in innovation. The early-stage pipeline includes 50
high potential assets, many with important data readouts in the
near-term. With a significantly enhanced early-stage pipeline,
Bristol-Myers Squibb will be well positioned for long-term growth and
significant value creation.
-
Powerful combined discovery capabilities with world-class expertise
in a broad range of modalities. Together, the Company will have
expanded innovation capabilities in small molecule design,
biologics/synthetic biologics, protein homeostasis, antibody
engineering and cell therapy. Furthermore, strong external
partnerships provide access to additional modalities.
Compelling Financial Benefits
-
Strong returns and significant immediate EPS accretion. The
transaction’s internal rate of return is expected to be well in excess
of Celgene’s and Bristol-Myers Squibb’s cost of capital. The
combination is expected to be more than 40 percent accretive to
Bristol-Myers Squibb’s EPS on a standalone basis in the first full
year following close of the transaction.
-
Strong balance sheet and cash flow generation to enable significant
investment in innovation. With more than $45 billion of expected
free cash flow generation over the first three full years
post-closing, the Company is committed to maintaining strong
investment grade credit ratings while continuing its dividend policy
for the benefit of Bristol-Myers Squibb and Celgene shareholders.
Bristol-Myers Squibb will also have significant financial flexibility
to realize the full potential of the enhanced late- and early-stage
pipeline.
-
Meaningful cost synergies. Bristol-Myers Squibb expects to
realize run-rate cost synergies of approximately $2.5 billion by 2022.
Bristol-Myers Squibb is confident it will achieve efficiencies across
the organization while maintaining a strong, core commitment to
innovation and delivering the value of the portfolio.
Terms and Financing
Based on the closing price of Bristol-Myers Squibb stock on January 2,
2019, the cash and stock consideration to be received by Celgene
shareholders is valued at $102.43 per share. The cash and stock
consideration represents an approximately 51 percent premium to Celgene
shareholders based on the 30-day volume weighted average closing stock
price of Celgene prior to signing and an approximately 54 percent
premium to Celgene shareholders based on the closing stock price of
Celgene on January 2, 2019. Each share also will receive one tradeable
CVR, which will entitle its holder to receive a one-time potential
payment of $9.00 in cash upon FDA approval of all three of ozanimod (by
December 31, 2020), liso-cel (JCAR017) (by December 31, 2020) and bb2121
(by March 31, 2021), in each case for a specified indication.
The transaction is not subject to a financing condition. The cash
portion will be funded through a combination of cash on hand and debt
financing. Bristol-Myers Squibb has obtained fully committed debt
financing from Morgan Stanley Senior Funding, Inc. and MUFG Bank, Ltd.
Following the close of the transaction, Bristol-Myers Squibb expects
that substantially all of the debt of the combined company will be pari
passu.
Accelerated Share Repurchase Program
Bristol-Myers Squibb expects to execute an accelerated share repurchase
program of up to approximately $5 billion, subject to the closing of the
transaction, market conditions and Board approval.
Corporate Governance
Following the close of the transaction, Dr. Caforio will continue to
serve as Chairman of the Board and Chief Executive Officer of the
company. Two members from Celgene’s Board will be added to the Board of
Directors of Bristol-Myers Squibb. The combined company will continue to
have a strong presence throughout New Jersey.
Approvals and Timing to Close
The transaction is subject to approval by Bristol-Myers Squibb and
Celgene shareholders and the satisfaction of customary closing
conditions and regulatory approvals. Bristol-Myers Squibb and Celgene
expect to complete the transaction in the third quarter of 2019.
Advisors
Morgan Stanley & Co. LLC is serving as lead financial advisor to
Bristol-Myers Squibb, and Evercore and Dyal Co. LLC are serving as
financial advisors to Bristol-Myers Squibb. Kirkland & Ellis LLP is
serving as Bristol-Myers Squibb’s legal counsel. J.P. Morgan Securities
LLC is serving as lead financial advisor and Citi is acting as financial
advisor to Celgene. Wachtell, Lipton, Rosen & Katz is serving as legal
counsel to Celgene.
Bristol-Myers Squibb 2019 EPS Guidance
In a separate press release issued today, Bristol-Myers Squibb announced
its 2019 EPS guidance for full-year 2019, which is available on the
“Investor Relations” section of the Bristol-Myers Squibb website at https://www.bms.com/investors.html.
Conference Call
Bristol-Myers Squibb and Celgene will host a conference call today, at
8:00 a.m. ET to discuss the transaction. The conference call can be
accessed by dialing (800) 347-6311 (U.S. / Canada) or (786) 460-7199
(International) and giving the passcode 4935567. A replay of the call
will be available from January 3, 2019 until January 17, 2019 by dialing
(888) 203-1112 (U.S. / Canada) or (719) 457-0820 (International) and
giving the passcode 4935567.
A live webcast of the conference call will be available on the investor
relations section of each company’s website at Bristol-Myers Squibb https://www.bms.com/investors.html
and Celgene https://ir.celgene.com/investors/default.aspx.
Presentation and Infographic
Associated presentation materials and an infographic regarding the
transaction will be available on the investor relations section of each
company’s website at Bristol-Myers Squibb https://www.bms.com/investors.html
and Celgene https://ir.celgene.com/investors/default.aspx
as well as a joint transaction website at www.bestofbiopharma.com.
About Bristol-Myers Squibb
Bristol-Myers Squibb is a global biopharmaceutical company whose mission
is to discover, develop and deliver innovative medicines that help
patients prevail over serious diseases. For more information about
Bristol-Myers Squibb, visit us at BMS.com or
follow us on LinkedIn,
Twitter,
YouTube
and Facebook.
About Celgene
Celgene Corporation, headquartered in Summit, New Jersey, is an
integrated global biopharmaceutical company engaged primarily in the
discovery, development and commercialization of innovative therapies for
the treatment of cancer and inflammatory diseases through
next-generation solutions in protein homeostasis, immuno-oncology,
epigenetics, immunology and neuro-inflammation. For more information,
please visit www.celgene.com.
Follow Celgene on Social Media: @Celgene,
Pinterest,
LinkedIn,
Facebook
and YouTube
Important Information For Investors And Stockholders
This communication does not constitute an offer to sell or the
solicitation of an offer to buy any securities or a solicitation of any
vote or approval. It does not constitute a prospectus or prospectus
equivalent document. No offering of securities shall be made except by
means of a prospectus meeting the requirements of Section 10 of the U.S.
Securities Act of 1933, as amended.
In connection with the proposed transaction between Bristol-Myers Squibb
Company (“Bristol-Myers Squibb”) and Celgene Corporation (“Celgene”),
Bristol-Myers Squibb and Celgene will file relevant materials with the
Securities and Exchange Commission (the “SEC”), including a
Bristol-Myers Squibb registration statement on Form S-4 that will
include a joint proxy statement of Bristol-Myers Squibb and Celgene that
also constitutes a prospectus of Bristol-Myers Squibb, and a definitive
joint proxy statement/prospectus will be mailed to stockholders of
Bristol-Myers Squibb and Celgene. INVESTORS AND SECURITY HOLDERS OF
BRISTOL-MYERS SQUIBB AND CELGENE ARE URGED TO READ THE JOINT PROXY
STATEMENT/PROSPECTUS AND OTHER DOCUMENTS THAT WILL BE FILED WITH THE SEC
CAREFULLY AND IN THEIR ENTIRETY WHEN THEY BECOME AVAILABLE BECAUSE THEY
WILL CONTAIN IMPORTANT INFORMATION. Investors and security holders will
be able to obtain free copies of the registration statement and the
joint proxy statement/prospectus (when available) and other documents
filed with the SEC by Bristol-Myers Squibb or Celgene through the
website maintained by the SEC at https://www.sec.gov/.
Copies of the documents filed with the SEC by Bristol-Myers Squibb will
be available free of charge on Bristol-Myers Squibb’s internet website
at https://www.bms.com/
under the tab, “Investors” and under the heading “Financial Reporting”
and subheading “SEC Filings” or by contacting Bristol-Myers Squibb’s
Investor Relations Department through https://www.bms.com/investors/investor-contacts.html.
Copies of the documents filed with the SEC by Celgene will be available
free of charge on Celgene’s internet website at https://www.celgene.com/
under the tab “Investors” and under the heading “Financial Information”
and subheading “SEC Filings” or by contacting Celgene’s Investor
Relations Department at ir@celgene.com.
Certain Information Regarding Participants
Bristol-Myers Squibb, Celgene, and their respective directors and
executive officers may be considered participants in the solicitation of
proxies in connection with the proposed transaction. Information about
the directors and executive officers of Bristol-Myers Squibb is set
forth in its Annual Report on Form 10-K for the year ended December 31,
2017, which was filed with the SEC on February 13, 2018, its proxy
statement for its 2018 annual meeting of stockholders, which was filed
with the SEC on March 22, 2018, and its Current Report on Form 8-K,
which was filed with the SEC on August 28, 2018. Information about the
directors and executive officers of Celgene is set forth in its Annual
Report on Form 10-K for the year ended December 31, 2017, which was
filed with the SEC on February 7, 2018, its proxy statement for its 2018
annual meeting of stockholders, which was filed with the SEC on April
30, 2018, and its Current Reports on Form 8-K, which were filed with the
SEC on June 1, 2018, June 19, 2018 and November 2, 2018. Other
information regarding the participants in the proxy solicitations and a
description of their direct and indirect interests, by security holdings
or otherwise, will be contained in the joint proxy statement/prospectus
and other relevant materials to be filed with the SEC regarding the
proposed transaction when they become available. You may obtain these
documents (when they become available) free of charge through the
website maintained by the SEC at http://www.sec.gov and from Investor
Relations at Bristol-Myers Squibb or Celgene as described above.
Cautionary Statement Regarding Forward-Looking Statements
This communication contains forward-looking statements within the
meaning of Section 27A of the Securities Act of 1933, as amended, and
Section 21E of the Securities Exchange Act of 1934, as amended. You can
generally identify forward-looking statements by the use of
forward-looking terminology such as “anticipate,” “believe,” “continue,”
“could,” “estimate,” “expect,” “explore,” “evaluate,” “intend,” “may,”
“might,” “plan,” “potential,” “predict,” “project,” “seek,” “should,” or
“will,” or the negative thereof or other variations thereon or
comparable terminology. These forward-looking statements are only
predictions and involve known and unknown risks and uncertainties, many
of which are beyond Bristol-Myers Squibb’s and Celgene’s control.
Statements in this communication regarding Bristol-Myers Squibb, Celgene
and the combined company that are forward-looking, including projections
as to the anticipated benefits of the proposed transaction, the impact
of the proposed transaction on Bristol-Myers Squibb’s and Celgene’s
business and future financial and operating results, the amount and
timing of synergies from the proposed transaction, the terms and scope
of the expected financing for the proposed transaction, the aggregate
amount of indebtedness of the combined company following the closing of
the proposed transaction, expectations regarding cash flow generation,
accretion to non-GAAP earnings per share, capital structure, debt
repayment, adjusted leverage ratio and credit ratings following the
closing of the proposed transaction, Bristol-Myers Squibb’s ability and
intent to conduct a share repurchase program and declare future dividend
payments, the combined company’s pipeline, intellectual property
protection and R&D spend, the timing and probability of a payment
pursuant to the contingent value right consideration, and the closing
date for the proposed transaction, are based on management’s estimates,
assumptions and projections, and are subject to significant
uncertainties and other factors, many of which are beyond Bristol-Myers
Squibb’s and Celgene’s control. These factors include, among other
things, effects of the continuing implementation of governmental laws
and regulations related to Medicare, Medicaid, Medicaid managed care
organizations and entities under the Public Health Service 340B program,
pharmaceutical rebates and reimbursement, market factors, competitive
product development and approvals, pricing controls and pressures
(including changes in rules and practices of managed care groups and
institutional and governmental purchasers), economic conditions such as
interest rate and currency exchange rate fluctuations, judicial
decisions, claims and concerns that may arise regarding the safety and
efficacy of in-line products and product candidates, changes to
wholesaler inventory levels, variability in data provided by third
parties, changes in, and interpretation of, governmental regulations and
legislation affecting domestic or foreign operations, including tax
obligations, changes to business or tax planning strategies,
difficulties and delays in product development, manufacturing or sales
including any potential future recalls, patent positions and the
ultimate outcome of any litigation matter. These factors also include
the combined company’s ability to execute successfully its strategic
plans, including its business development strategy, the expiration of
patents or data protection on certain products, including assumptions
about the combined company’s ability to retain patent exclusivity of
certain products, the impact and result of governmental investigations,
the combined company’s ability to obtain necessary regulatory approvals
or obtaining these without delay, the risk that the combined company’s
products prove to be commercially successful or that contractual
milestones will be achieved. Similarly, there are uncertainties relating
to a number of other important factors, including: results of clinical
trials and preclinical studies, including subsequent analysis of
existing data and new data received from ongoing and future studies; the
content and timing of decisions made by the U.S. FDA and other
regulatory authorities, investigational review boards at clinical trial
sites and publication review bodies; the ability to enroll patients in
planned clinical trials; unplanned cash requirements and expenditures;
competitive factors; the ability to obtain, maintain and enforce patent
and other intellectual property protection for any product candidates;
the ability to maintain key collaborations; and general economic and
market conditions. Additional information concerning these risks,
uncertainties and assumptions can be found in Bristol-Myers Squibb’s and
Celgene’s respective filings with the SEC, including the risk factors
discussed in Bristol-Myers Squibb’s and Celgene’s most recent Annual
Reports on Form 10-K, as updated by their Quarterly Reports on Form 10-Q
and future filings with the SEC. It should also be noted that projected
financial information for the combined businesses of Bristol-Myers
Squibb and Celgene is based on management’s estimates, assumptions and
projections and has not been prepared in conformance with the applicable
accounting requirements of Regulation S-X relating to pro forma
financial information, and the required pro forma adjustments have not
been applied and are not reflected therein. None of this information
should be considered in isolation from, or as a substitute for, the
historical financial statements of Bristol-Myers Squibb or Celgene.
Important risk factors could cause actual future results and other
future events to differ materially from those currently estimated by
management, including, but not limited to, the risks that: a condition
to the closing of the proposed acquisition may not be satisfied; a
regulatory approval that may be required for the proposed acquisition is
delayed, is not obtained or is obtained subject to conditions that are
not anticipated; Bristol-Myers Squibb is unable to achieve the synergies
and value creation contemplated by the proposed acquisition;
Bristol-Myers Squibb is unable to promptly and effectively integrate
Celgene’s businesses; management’s time and attention is diverted on
transaction-related issues; disruption from the transaction makes it
more difficult to maintain business, contractual and operational
relationships; the credit ratings of the combined company declines
following the proposed acquisition; legal proceedings are instituted
against Bristol-Myers Squibb, Celgene or the combined company;
Bristol-Myers Squibb, Celgene or the combined company is unable to
retain key personnel; and the announcement or the consummation of the
proposed acquisition has a negative effect on the market price of the
capital stock of Bristol-Myers Squibb and Celgene or on Bristol-Myers
Squibb’s and Celgene’s operating results. No assurances can be given
that any of the events anticipated by the forward-looking statements
will transpire or occur, or if any of them do occur, what impact they
will have on the results of operations, financial condition or cash
flows of Bristol-Myers Squibb or Celgene. Should any risks and
uncertainties develop into actual events, these developments could have
a material adverse effect on the proposed transaction and/or
Bristol-Myers Squibb or Celgene, Bristol-Myers Squibb’s ability to
successfully complete the proposed transaction and/or realize the
expected benefits from the proposed transaction. You are cautioned not
to rely on Bristol-Myers Squibb’s and Celgene’s forward-looking
statements. These forward-looking statements are and will be based upon
management’s then-current views and assumptions regarding future events
and operating performance, and are applicable only as of the dates of
such statements. Neither Bristol-Myers Squibb nor Celgene assumes any
duty to update or revise forward-looking statements, whether as a result
of new information, future events or otherwise, as of any future date.
BRISTOL-MYERS SQUIBB Media:Laura Hortas609-252-4587 laura.hortas@bms.com Investors:Tim Power609-252-7509 timothy.power@bms.com CELGENE Investors:908-673-9628 ir@celgene.com orMedia:908-673-2275 media@celgene.com