Bristol-Myers
Squibb Company (NYSE:BMY) and Dana-Farber Cancer Institute today
announced that they have entered into a research collaboration agreement
as part of the Immuno-Oncology Rare Population Malignancy (I-O RPM)
program in the U.S. Dana-Farber Cancer Institute is the latest leading,
academic-based cancer center to join the I-O RPM program, which is a
multi-institutional initiative focused on the clinical investigation of
immuno-oncology therapeutics as potential treatment options for patients
with high risk, poor prognostic cancers, defined as a rare population
malignancy.
“Dana-Farber Cancer Institute and Bristol-Myers Squibb have a shared
commitment to patients and to continuing to advance the science in
Immuno-Oncology research,” said Laura Bessen, MD, head of U.S. Medical,
Bristol-Myers Squibb. “We look forward to working with them as part of
the I-O RPM program.”
“Recent advances in scientific research have shown the great potential
of immuno-oncology agents in hematologic cancers, including myeloma,”
commented Dr. Paul Richardson, Clinical Program Leader and Director of
Clinical Research of the Jerome Lipper Multiple Myeloma Center at
Dana-Farber Cancer Institute. “We look forward to expanding on these
findings through the support of the I-O RPM program with the goal of
further improving patient outcomes.”
As part of the I-O RPM program, Bristol-Myers Squibb and Dana-Farber
Cancer Institute will conduct a range of early phase clinical studies
and Bristol-Myers Squibb will support the training of young
investigators who contribute to the I-O RPM program at Dana-Farber.
About I-O RPM
Immuno-oncology is an innovative approach to cancer research and
treatment that is designed to harness the body’s own immune system to
fight cancer. The I-O RPM research program focuses on significant areas
of high unmet need marked by poor outcomes among patients with rare
population malignancies. A rare population malignancy is a subpopulation
within a higher incident disease population. These patients have
aggressive disease with an increased potential for early metastasis to
multiple sites and/or are initially refractory or subject to early
recurrences with conventional cancer therapies. Existing clinical
research provide a strong rationale for further research into the
potential of immunotherapies for these cancers.
The I-O RPM research program is a multi-institutional initiative with
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
and the Northwestern Medicine Developmental Therapeutics Institute,
Moffitt Cancer Center, Johns Hopkins Kimmel Cancer Center and now the
Dana-Farber Cancer Institute. I-O RPM builds on Bristol-Myers Squibb’s
formation in 2012 of the International Immuno-Oncology Network (II-ON),
which is a global collaboration between Bristol-Myers Squibb and
academia focused on facilitating the translation of scientific research
findings into clinical trials and, eventually, clinical practice.
About Bristol Myers Squibb
Bristol-Myers Squibb is a global biopharmaceutical company whose mission
is to discover, develop and deliver innovative medicines that help
patients prevail over serious diseases. For more information about
Bristol-Myers Squibb, visit us at BMS.com
or follow us on LinkedIn,
Twitter,
and YouTube.
About the Dana-Farber Cancer Institute
Dana-Farber
Cancer Institute, a principal teaching affiliate of Harvard Medical
School, is world-renowned for its leadership in adult and pediatric
cancer treatment and research. Designated as a comprehensive cancer
center by the National Cancer Institute (NCI), it is one of the largest
recipients among independent hospitals of NCI and National Institutes of
Health grant funding. For more information, go to www.dana-farber.org.
Bristol-Myers Squibb Forward-Looking Statement
This press release contains “forward-looking statements” as that term
is defined in the Private Securities Litigation Reform Act of 1995
regarding the research, development and commercialization of
pharmaceutical products. Such forward-looking statements are based on
current expectations and involve inherent risks and uncertainties,
including factors that could delay, divert or change any of them, and
could cause actual outcomes and results to differ materially from
current expectations. No forward-looking statement can be guaranteed.
Among other risks, there can be no guarantee that the immuno-oncology
therapeutics discussed in this release will be successfully developed or
approved for any of the indications described in this release, such as
multiple myeloma and other hematologic malignancies. Forward-looking
statements in this press release should be evaluated together with the
many uncertainties that affect Bristol-Myers Squibb's business,
particularly those identified in the cautionary factors discussion in
Bristol-Myers Squibb's Annual Report on Form 10-K for the year ended
December 31, 2014 in our Quarterly Reports on Form 10-Q and our Current
Reports on Form 8-K. Bristol-Myers Squibb undertakes no obligation to
publicly update any forward-looking statement, whether as a result of
new information, future events or otherwise.
Bristol-Myers SquibbMedia:Sarah Koenig, 609-252-4145sarah.koenig@bms.comorInvestors:Ranya Dajani, 609-252-5330ranya.dajani@bms.comorBill Szablewski, 609-252-5894william.szablewski@bms.comorDana-Farber Cancer InstituteMedia:Teresa Herbert, 617-632-4090Teresa_Herbert@dfci.harvard.edu