Corporate news details

First Phase III Data on Innovative Compound for Solid Organ Transplantation To be Featured at American Transplant Congress

May 28, 2009

Nine Clinical Presentations to Highlight Belatacept

NEW YORK--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) announced today that belatacept, an investigational co-stimulation blocker being studied for use in solid organ transplantation, will be the subject of nine company-sponsored clinical presentations at the upcoming American Transplant Congress to be held May 30 to June 3 in Boston. Belatacept is in phase III development.

“Bristol-Myers Squibb is committed to developing innovative therapies to address significant unmet medical needs,” said Elliott Sigal, M.D., Ph.D., executive vice president, chief scientific officer and president, Research and Development, Bristol-Myers Squibb. “We are pleased to share our belatacept phase III data for the first time at an important scientific conference for transplant professionals.”

       

The times, titles and lead authors of the phase III data presentations are as follows:

             
Date/Time     Presentation Title     Lead Author
May 30, 5:30 p.m. ET    

Belatacept Demonstrates Superior Composite Patient/Graft Survival in

Diabetic Kidney Transplant Recipients vs. CsA: Results from the

BENEFIT and BENEFIT-EXT Studies

 

    L. Rostaing

Univ. Hospital

Toulouse, France

May 31, 9:15 a.m. ET    

Primary Outcomes from a Randomized, Phase III Study of

Belatacept vs. Cyclosporine in Kidney Transplant Recipients

(BENEFIT Study)

 

    F. Vincenti

UCSF

San Francisco, CA

May 31, 2:15 p.m. ET    

Primary Outcomes from a Randomized, Phase III Study of

Belatacept vs. Cyclosporine in ECD Kidney Transplants

(BENEFIT-EXT Study)

 

   

A. Durrbach

Bicêtre Hospital, Kremlin

Bicêtre, France

May 31, 2:27 p.m. ET    

Belatacept is Associated with Preservation of Renal Function and

Structure at 1 Year Compared to Cyclosporine in Extended Criteria

Donor (ECD) Kidney Transplant Patients (BENEFIT-EXT Study)

 

    J. Medina Pestana

Hospital do Rim e Hipertensão Unifesp

Sao Paulo, Brazil

May 31, 4:36 p.m. ET    

Renal Benefit of Belatacept vs. Cyclosporine in Kidney Transplant

Patients is Not Impacted by Acute Rejection

(BENEFIT Study)

 

    C. Larsen

Emory University

Atlanta, GA

May 31, 5:30 p.m. ET    

Belatacept is Associated with Improved Cardiovascular and

Metabolic Risk Factors Compared to Cyclosporine in Kidney Transplant

Patients (BENEFIT and BENEFIT-EXT Studies)

 

   

Y. Vanrenterghem

Univ. Hospital Leuven,

Leuven, Belgium

May 31, 5:30 p.m. ET    

One Year Safety Profile of Belatacept in Kidney Transplant Patients

from the BENEFIT and BENEFIT-EXT Studies

 

   

C. Larsen

Emory University

Atlanta, GA

 

June 1, 2:27 p.m. ET    

Belatacept is Associated with Preservation of Renal Function and

Structure at 1 Year Compared to Cyclosporine in Kidney Transplant

Patients (BENEFIT Study)

 

    J. Grinyó

University Hospital of Bellvitge

Barcelona, Spain

 

In addition, there is one phase II presentation on belatacept at the conference:

             

June 3, 10:27 a.m. ET

   

Immunosuppression with Belatacept-Based, CNI-Free, Steroid-Avoiding

Regimens in Kidney Transplant Recipients: 6 Month, Interim Results

 

   

J. Grinyó

University Hospital of Bellvitge

Barcelona, Spain

 

About Bristol-Myers Squibb

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to extend and enhance human life.

Bristol-Myers Squibb CompanyMedia:Brian Henry, 609-252-3337brian.henry@bms.comorInvestors:John Elicker, 609-252-4611john.elicker@bms.com

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